Country: Georgia   -  Stage: 2

MDR-TB burden: 15 per 100,000
No. of trial sites: 1
Date first patient recruited: October 2017
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Tuberculosis remains a major public health challenge in Georgia. In 2017, estimated incidence for TB was 86 per 100 000 population and the mortality rate was 5.6 per 100 000 population. In the same year, 2,927 TB cases were notified. It is also estimated that 11% of new cases and 30% of previously treated cases were MDR/RR-TB. In 2015, MDR/RR-TB treatment was initiated in 412 patients, of which 56% were successfully treated.

Given the significant MDR-TB burden in Georgia, the National Center for Tuberculosis and Lung Diseases (NCTLD) in Tbilisi was selected to participate in Stage 2 of the trial. Georgia is the fifth country and the eighth site to initiate STREAM Stage 2. NCTLD is currently expected to complete recruitment in late 2019 and enroll more than 35 participants for Stage 2.

The NCTLD was founded in 2001 as a non-profit organization that combined the Institute of Tuberculosis and Lung Disease, Tbilisi’s TB Hospital, and the Georgian Railway TB-Stationary. The NCTLD designed and currently oversees implementation of the National Tuberculosis Program at health facilities throughout the country. It also provides TB prevention, diagnosis, and treatment.